Post-Exposure Prophylaxis (PEP) for HIV


First Published:
June 2023
Last Updated:
June 2023
Resource Type:

Resource overview

These guidelines outline the management of individuals who have been exposed (or suspect they have been exposed) to HIV in non-occupational and occupational settings. Every presentation for PEP should be assessed on a case-by-case basis, balancing the potential harms and benefits of treatment.

Recommendations following non-occupational exposure have been updated, and information about PEP in the context of pre-exposure prophylaxis (PrEP), PEP and children, renal disease, and gender identity and
history has been added.

To support you with the implementation of these guidelines the following template documents have been prepared as part of the 2016 review. The Expert Reference Group for the guidelines thanks the staff at the Western NSW LHD and St Vincent’s Hospital in Sydney, for providing their materials for adaptation for this purpose.

Please note: these resources are provided as templates for adaptation in line with local protocols. Finalised content is the responsibility of local staff.

Available Resources:

PEP Literature Review (PDF)
PEP Guidelines Poster (PDF)
PEP Checklist
NPEP Procedure Flowchart Template
NPEP Patient Information Sheet
NPEP Referral Letter Proforma

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